13148_2021_1043_MOESM14_ESM.xlsx (2.42 MB)
Additional file 14 of Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations
dataset
posted on 2021-03-25, 08:38 authored by J. Pei, M. Schuldt, E. Nagyova, Z. Gu, S. el Bouhaddani, L. Yiangou, M. Jansen, J. J. A. Calis, L. M. Dorsch, C. Snijders Blok, N. A. M. van den Dungen, N. Lansu, B. J. Boukens, I. R. Efimov, M. Michels, M. C. Verhaar, R. de Weger, A. Vink, F. G. van Steenbeek, A. F. Baas, R. P. Davis, H. W. Uh, D. W. D. Kuster, C. Cheng, M. Mokry, J. van der Velden, F. W. Asselbergs, M. HarakalovaAdditional file 14: Table S6 (A) The overlapping genes between differentially expressed genes using DESeq2 and the top 2,000 genes that discriminate HCM from control hearts using O2PLS. (B) Enriched GO terms and pathways by the overlapping genes. (C) Enriched GO terms and pathways by a subset of the overlapping genes, which showed the same changing direction at their protein levels in HCM hearts when compared with controls
