Additional file 13 of Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

dataset

posted on 2021-03-25, 08:38 authored by J. Pei, M. Schuldt, E. Nagyova, Z. Gu, S. el Bouhaddani, L. Yiangou, M. Jansen, J. J. A. Calis, L. M. Dorsch, C. Snijders Blok, N. A. M. van den Dungen, N. Lansu, B. J. Boukens, I. R. Efimov, M. Michels, M. C. Verhaar, R. de Weger, A. Vink, F. G. van Steenbeek, A. F. Baas, R. P. Davis, H. W. Uh, D. W. D. Kuster, C. Cheng, M. Mokry, J. van der Velden, F. W. Asselbergs, M. Harakalova

Additional file 13: Table S5 (A) Unsupervised analysis (O2PLS) ranking DNA regions that contributed to the separation between HCM and control hearts. (B) Unsupervised analysis (O2PLS) ranking genes that contributed to the separation between HCM and control hearts

Funding

The Netherlands Foundation for Cardiovascular Excellence NWO VENI grant NWO VIDI grant ZonMW-NWO VICI grant Erasmus MC fellowship grant RM fellowship grant of the UMC Utrecht Wilhelmina Children’s Hospital research funding Netherlands Cardiovascular Research Initiative: An initiative with the support of the Dutch Heart Foundation UCL Hospitals NIHR Biomedical Research Centre H2020 European Research Council

History

Usage metrics

Keywords

HCM MYBPC3 Histone acetylome Transcriptome Proteome Transcription factors

Licence

CC BY + CC0

Exports

RefWorks

BibTeX

Ref. manager

Endnote

DataCite

NLM