13059_2021_2560_MOESM13_ESM.xlsx (31.59 kB)
Additional file 13 of Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations
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posted on 2022-01-08, 04:24 authored by Charles E. Breeze, Eric Haugen, Alex Reynolds, Andrew Teschendorff, Jenny van Dongen, Qing Lan, Nathaniel Rothman, Guillaume Bourque, Ian Dunham, Stephan Beck, John Stamatoyannopoulos, Nora Franceschini, Sonja I. BerndtAdditional file 13: Table S12. FORGE2 DNase I hotspot analysis results (q-values) for a set of 25 variants from a GWAS on myeloproliferative neoplasms.
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underlying regulatory mechanismssingle nucleotide polymorphismsfriendly web toolforge web toolactive regulatory elementsspecific repressed regionsspecific regulatory elementswide association study60 associations specific400 associations specific30 associations specificrepressive chromatin statesdifferent chromatin stateshttps :// forge2cell types relevantassociated cell typemediated disease aetiologychromatin statescell typescell typedisease aetiologyspecific signalsspecific regulationspecific enrichmentstissue associationsdisease risktissue associationupdated versionpreferentially coloci discoveredhistone marksgain insightforge2 usesexpanded atlasepigenomic marksdeveloped forge2also detected
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