13046_2020_1773_MOESM11_ESM.xlsx (70.65 kB)
Additional file 11 of Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma
dataset
posted on 2020-11-26, 05:30 authored by Shejuan An, Jeannie M. Camarillo, Tina Yi-Ting Huang, Daphne Li, Juliette A. Morris, Madeline A. Zoltek, Jin Qi, Mandana Behbahani, Madhuri Kambhampati, Neil L. Kelleher, Javad Nazarian, Paul M. Thomas, Amanda M. SaratsisAdditional file 11: S11. Validation of changes in H3K27M and H3K27Ac in DIPG cells after Bromodomain inhibition. A Western blot of extracted histones for H3K27M and H3K27Ac from DIPG cell lines SF8628 and DIPG007 after 24 h of Bromodomain inhibition was performed in triplicate and compared to DMSO treated controls. B, C Bar graphs depicting mean OD value ± SEM across replicates for each treatment group, with p-values for between group comparisons (Independent-sample t test, two-tailed).
