Sarcopenia characteristics, bioimpedance measurements and clinical data on kidney transplant recipients

This metadata record consists of one data file, Datarev.xlsx,in Excel file format. The table shows characteristics, clinical data, BMI, bioimpedance measurements and muscle strength and physical performance measurements of 210 kidney transplant recipients.

The Excel table consists of 32 columns and 31 measured parameters. The first column refers to the patient number. The measured parameters are:
-Height [cm]: Height of patient, measured in centimeters
-Weight [kg]: Weight of patient, measured in kilograms.
-BMI [Kg/m2]: Body mass index, measured in kilograms per squared meter, Kg/m2.
-Donor type (deceased 0/living 1): 0:The kidney transplant recipient has received a kidney from a deceased donor. 1: The kidney transplant recipient has received a kidney from a living donor.
-ABO-incompatible KT: ABO-incompatible kidney transplant; 0: donor's blood type and recipient's blood type are compatible. 1: donor's blood type and recipient's blood type are incompatible.
-Calcineurin inhibitor (cyclosporine 0/ tacrolimus 1): The calcineurin inhibitors cyclosporine and tacrolimus are used as immunosuppressive agents for renal transplantation. 0: kidney transplant patient was administered with cyclosporine. 1: kidney transplant patient was administered with tacrolimus.
-Antimetabolites or everolimus: Antimetabolites and everolimus are immunosuppressant drugs used to prevent the rejection of organ transplants. MMF: Mycophenolate mofetil, EVR: Everolimus, AZ: Azathioprine, MZR: Mizoribine.
-Diabetes Mellitus: 0: absence of diabetes mellitus in kidney transplant recipient. 1: presence of diabetes mellitus in kidney transplant recipient.
-Hypertension: 0: absence of hypertension in kidney transplant recipient. 1: presence of hypertension in kidney transplant recipient.
-Handgrip strength [Kg]: Handgrip strength was used as a measure of muscle strength and as a diagnostic riterion for sarcopenia. Handgrip strength was measured in kilograms, Kg.
-Gait speed [m/s]: The gait speed of kidney transplant recipients was measured as the time taken to walk 10 meters, and the average time of two trials was taken. Gait speed was measured in meters per second, m/s.
- Skeletal muscle mass index [Kg/m2]: Skeletal muscle mass index was used as a criterion for sarcopenia diagnosis. Skeletal muscle mass index was measured in kilograms per squared meter, Kg/m2.
-Gait speed <0.8: Gait speed was measured in meters per second, m/s. Low functional capacity was defined as gait speed < 0.8 m/s. 0: kidney transplant recipient with gait speed >0.8 m/s. 1: kidney transplant recipient with gait speed <0.8 m/s.
-Handgrip strength <26 (male), <18 (female): Handgrip strength was measured in Kilograms, Kg. Low muscle strength was defined as handgrip strength <26 Kg for males and <18 Kg for females. 0: kidney transplant recipient with handgrip strength >26 Kg (male) or >18 Kg (female). 1: kidney transplant recipient with handgrip strength <26 Kg (male) or <18 Kg (female).
-Skeletal muscle mass index <7.0 (male), <5.7 (female):
Skeletal muscle mass index was measured in kilograms per squared meter, Kg/m2. Low muscle mass was defined as skeletal muscle mass index (SMI) <7.0 Kg/m2 for males and <5.7 Kg/m2 for females. 0: kidney transplant recipient with skeletal muscle mass index of >0.7Kg/m2 (male) or >5.7 Kg/m2 (female). 1: kidney transplant recipient with skeletal muscle mass index of <0.7Kg/m2 (male) or <5.7 Kg/m2 (female).
-Sarcopenia: 0: Absence of sarcopenia in kidney transplant recipient. 1: Presence of sarcopenia in kidney transplant recipient.
-Hb: Haemoglobin, measured in grams per liter of blood, g/L.
-Alb: Serum albumin, measured in grams per liter of blood, g/L.
-FBS: Fasting blood sugar levels, measured in milligrams per deciliter, mg/dL.
-sCr: Serum creatinine, measured in milligrams per deciliter mg/dL.
-cys-C: Serum cystatin C, measured in milligrams per deciliter mg/dL.
-eGFR: Estimated glumerular filtration rate, measured in milliliters per minute per 1.73m2. 1.73m2 corresponds to the body surface area of an average-sized man.
-HbA1C: Hemoglobin A1c levels. HbA1c is glycated hemoglobin, a form of hemoglobin covalently bound to glucose, measured as a percentage of total hemoglobin.
-Ca: Calcium levels, measured in milligrams per deciliter mg/dL.
-P: Phosphorus levels, measured in milligrams per deciliter mg/dL.
-HDL: High-density lipoprotein, measured in milligrams per deciliter mg/dL.
-LDL: Low-density lipoprotein, measured in milligrams per deciliter mg/dL.
-TG: Triglyceride levels, measured in milligrams per deciliter mg/dL.
-Phase Angle˚: Phase angle determined from bioelectrical impedance in kidney transplant recipients, measured in degrees, ˚.
-Total body water/lean mass: Ratio of total body water to lean mass, expressed as a percentage.
-CRP: C-reactive protein, measured in milligrams per deciliter (mg/dL).

This is a single-center cross-sectional study conducted among kidney transplant recipients as Osaka City University Hospital between October 2018 and February 2019.
The aims of this study were:
1. To investigate the prevalence of sarcopenia and the relationship between sarcopenia and phase angle as well as other nutritional indicators such as BMI and albumin levels in kidney transplant recipients.
2. To evaluate the discrimination performance of these nutritional indicators for sarcopenia in kidney transplant recipients.
A total of 210 kidney transplant recipients were enrolled in this study.
Sarcopenia was diagnosed by low muscle mass (skeletal muscle mass index) and either low muscle strength (handgrip strength) or low physical performance.
Muscle strength and physical performance measurements (such as gait speed) and bioimpedance (skeletal muscle mass and phase angle) and biochemical measurements (such as hemoglobin and albumin levels) were also taken.
Categorical variables were expressed as count and percentage, and continuous variables were expressed as median and interquartile range (IQR). Categorical variables were compared using chi-squared test, and continuous variables were compared using Mann-Whitney U-test.
For more details on the methodology, please see the related publication.