MOESM9 of Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning

Additional file 9. Nucleosome fuzziness in the wt and dst1∆. A) The metagene analysis of the fuzziness score of the wt (blue) and dst1∆ (red) nucleosomes around the TSS. Genes were scaled to the same length and then aligned to their TSS. B) The change in fuzziness score between the wt and dst1∆. Heat map of the fuzziness score of the gene body nucleosomes in the wt and dst1∆ mutant. Color represents density, which increases from blue to red. The red square highlights those nucleosomes below 40 in the wt and above > 40 in the mutant. C) The fuzziness score distribution of the nucleosomes in the gene bodies of the highly transcribed genes of the wt (blue) and dst1∆ (red). D) The fuzziness score distribution of the nucleosomes in the promoters of the highly transcribed genes of the wt (blue) and dst1∆ (red).