Springer Nature
Browse
40478_2020_881_MOESM9_ESM.mp4 (2.57 MB)

MOESM9 of A robust TDP-43 knock-in mouse model of ALS

Download (2.57 MB)
media
posted on 2020-01-22, 08:36 authored by Shih-Ling Huang, Lien-Szu Wu, Min Lee, Chin-Wen Chang, Wei-Cheng Cheng, Yu-Sheng Fang, Yun-Ru Chen, Pei-Lin Cheng, Che-Kun Shen
Additional file 9: Movie S1. 18-month old N390D/+ mouse (#108). Note the 18-month old N390D/+ mice (Additional file 9: Movie S1 and Additional file 10: Movie S2) but not +/+ littermate (Additional file 11: Movie S3) exhibit spastic and tremble gait. Some of them show difficult movement due to paralysis of the hind limbs (Additional file 10: Movie S2).

History

Usage metrics

    Acta Neuropathologica Communications

    Categories

    Keywords

    Amyotrophic lateral sclerosis (ALS)TAR DNA-binding protein 43 (TDP-43)Homologous knock-in mouse models with ALS-associated TDP-43 mutationsALS-TDP pathogenesisAutonomous spinal cord motor neuron degenerationMis-splicing of Bcl-2 pre-mRNA

    Licence

    CC BY + CC0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC