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MOESM9 of ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia

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posted on 2019-05-22, 05:00 authored by William Swindell, Colin Kruse, Edward List, Darlene Berryman, John Kopchick
Additional file 9. Signature gene expression in 12 cell types. (A) Erythroid lineage. (B) Platelets. (C) CD4 + T cells. (D) NK cells. (E) CD8 + T cells. (F) B cells. (G) Macrophages. (H) Monocytes. (I) Dendritic cells. (J) Neutrophils. (K) Eosinophils. (L) Gamma-delta T cells. In (A)–(L), expression is shown for the 100 signature genes identified for each cell type. Boxes outline average expression among samples for the middle 50% of signature genes (midline: median expression). Median expression for each cell type is listed in the top margin. Relative gene expression is normalized to an average value of 1 across the 12 cell types.

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