MOESM7 of p66ShcA functions as a contextual promoter of breast cancer metastasis

Additional file 7: Figure S7. A p66ShcA-induced epithelial to mesenchymal transition is dispensable for metastatic progression in a luminal breast cancer model. Immunohistochemical analysis of vector control (VC), p66ShcA-WT and p66ShcA-S36A overexpressing NIC mammary tumors using (A) E-Cadherin and (B) Vimentin-specific antibodies. The data is shown as average tumor volume (mm3) ± SEM (n = 7 tumors/group). Representative images are shown. Statistical analysis was performed using a one-way Anova with a Tukey’s multiple comparisons test (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).