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MOESM7 of Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells

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posted on 2019-10-11, 05:37 authored by Fujun Li, Lixia Miao, Teng Xue, Hao Qin, Santanu Mondal, Paul Thompson, Scott Coonrod, Xiaoqiu Liu, Xuesen Zhang
Additional file 7. Figure S7. Western blot analysis showing that pretreatment of PAD2 knockdown (a) or miR-125b-5p overexpression (b) MCF7/TamR cells with 10 ÎźM MHY1485 abolished the inhibitory effect of docetaxel on Rps6 activation. GAPDH served as loading control; shPAD2: PAD2 knockdown MCF7/TamR cells; miR-125b-5p: miR-125b-5p overexpression MCF7/TamR cells; Doc: docetaxel; PBS was used as a control.

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National Key Research and Development Program of China

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    Journal of Experimental & Clinical Cancer Research

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    Breast cancerTamoxifen-resistancePAD2Docetaxel

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