MOESM6 of Human-specific mutations in VMAT1 confer functional changes and multi-directional evolution in the regulation of monoamine circuits

Additional file 6: Figure S2. Mean relative (a) density and (b) size of vesicles expressing the YFP-VMAT1 variants. All values are shown as the fold change relative to that of the 130Gly/136Ile variant (without reserpine). No significant differences were observed among variants in either comparison (P-values calculated by one-way ANOVA: 0.39 and 0.54, respectively).