MOESM5 of Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response

Additional file 5: Fig. S5. The mRNA vaccine (5–50 µg/106 cells) and R848 (5 µg/ml) drive cytokine production indicative of TLR activation (A) IFNα, (B) IL-12(p70), (C) IL-6. Mean ± SEM are shown for n = 24 subjects examined in MIMIC® modules.