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MOESM5 of A novel resveratrol derivative induces mitotic arrest, centrosome fragmentation and cancer cell death by inhibiting γ-tubulin

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posted on 2019-04-10, 05:00 authored by Gianandrea Traversi, David Staid, Mario Fiore, Zulema Percario, Daniela Trisciuoglio, Roberto Antonioletti, Veronica Morea, Francesca Degrassi, Renata Cozzi
Additional file 5: Figure S5. Comparison of colchicine binding to γ/γ- and α/β-tubulin dimer. β- and γ-tubulin are shown as ribbon and coloured dark green and cyan, respectively. Only β-tubulin and the structurally corresponding γ-tubulin monomers are shown, for clarity. Colchicine ligands are shown as sticks and coloured by atom type: N, blue; O, red; P, orange; C, yellow for colchicine imported from α/β-tubulin crystal structure to the homology model, and white for colchicine docked to γ-tubulin.

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