MOESM4 of Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes
2017-09-22T05:00:00Z (GMT) by
Additional file 4: Figure S2. Binding activities of other anti-CD4i mAbs against gp120 mutants. The binding activities of other anti-CD4i mAbs against gp120 were measured by gp120 capture ELISA. We used the monomeric gp120 of WT and eight mutants as described in Fig.Â 7. The binding activities of anti-CD4i mAbs in the presence (orange) or absence (blue) of sCD4 and anti-CD4bs mAb, 49G2 (gray) are shown.