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MOESM4 of The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16

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posted on 2019-06-17, 05:00 authored by Christian Arenas-López, Jessica Locker, Diego Orol, Frederik Walter, Tobias Busche, Jörn Kalinowski, Nigel Minton, Katalin Kovács, Klaus Winzer
Additional file 4: Figure S3. Differential expression of key metabolic genes in C. necator H16 during exponential phase growth on 3-HP and fructose, respectively. Red and green boxes indicate genes significantly up- and downregulated respectively, when cells were grown on 3-HP (padj <0.05). Grey boxes indicate no statistically significant differential regulation. Locus tags are given to enable unambiguous gene identification. Abbreviations: F6P, fructose-6-phosphate; G6P, glucose-6-phosphate; 6PGL, 6-phosphogluconolactone; 6PG, 6-phosphogluconate; KDPG, 2-keto-3-deoxy-6-phosphogluconate; FBP, fructose-1,6-bisphosphate; GAP, glyceraldehyde-3-phosphate, DHAP, dihydroxyacetone phosphate; S7P, sedoheptulose-7-phosphate; R5P, ribose-5-phosphate; X5P, xylulose-5-phosphate; E4P, erythrose-4-phosphate; 1,3PG, 1,3-phosphoglycerate; 3PG, 3-phosphoglycerate; 2PG, 2-phosphoglycerate; PEP, phosphoenolpyruvate; PYR, pyruvate; AcCoA, acetyl-CoA, CIT, citrate; ISOCIT, isocitrate, AKG, α-ketoglutarate; SUCC, succinate; FUM, fumarate; MAL, malate, OAA, oxaloacetate; GLYOX, glyoxylate; 3HP, 3-hydroxypropionate; MSA, malonate semialdehyde; 3HP-CoA, 3-hydroxypropionyl-CoA; AcrCoA, acryloyl-CoA; 3Prp-CoA, propionyl-CoA; MeCIT, methylcitrate; MeISOCIT, methylisocitrate.

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Biotechnology and Biological Sciences Research Council

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