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MOESM4 of Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells

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posted on 2019-11-13, 05:06 authored by William Gwynne, Mirza Shakeel, Jianhan Wu, Robin Hallett, Adele Girgis-Gabardo, Anna Dvorkin-Gheva, John Hassell
Additional file 4. MCF-7 human breast tumor cells form bona fide tumorspheres, whereas MDA-MB-231 form cellular aggregates. Images taken of MDA-MB-231 cells (top) and MCF-7 cells (bottom) grown in chemically defined media as tumorspheres. Tumorspheres were imaged at 100X magnification and the scale bar represents 100 μm. The arrows demarcate examples of a bona fide tumorspheres (solid arrows) and cellular aggregates (dashed arrows). (B) Examples of each structure shown at a higher magnification (200X).

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Canadian Institutes of Health Research

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