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MOESM3 of Unique binding modes for the broad neutralizing activity of single-chain variable fragments (scFv) targeting CD4-induced epitopes

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posted on 2017-09-22, 05:00 authored by Kazuki Tanaka, Takeo Kuwata, Muntasir Alam, Gilad Kaplan, Shokichi Takahama, Kristel Valdez, Anna Roitburd-Berman, Jonathan Gershoni, Shuzo Matsushita
Additional file 3: Figure S1. Binding enhancement of mAbs and their fragments to Env of BaL strain in the presence of sCD4. Binding activity to 293T cells expressing Env of BaL was examined using flow cytometry. Histogram of fluorescence intensity shows the binding of the mAbs as described in Fig. 4.

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Ministry of Education, Culture, Sports, Science and Technology

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    Retrovirology

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    HIV-1 neutralizing antibodyscFvCD4i epitopesBridging sheet

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