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MOESM3 of Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination

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posted on 2020-01-21, 05:13 authored by Hirotaka Asai, Noriaki Ohkawa, Yoshito Saitoh, Khaled Ghandour, Emi Murayama, Hirofumi Nishizono, Mina Matsuo, Teruyoshi Hirayama, Ryosuke Kaneko, Shin-ichi Muramatsu, Takeshi Yagi, Kaoru Inokuchi
Additional file 3: Figure S3. Pcdhβ deficiency does not affect neural activity at the cellular level (related to Figs. 1 and 2, and additional file 1). (a–b) Representative images of raster plots of all recorded cells from Wt (a) and Δβ (b) mice. (c) Cumulative curve of proportion of cells against number of active events during entire recording session (pre 10 min + sq 10 min). Proportions of cells according to the number of Ca2+ events during pre (d) and sq (e) sessions. Statistical values from Bonferroni’s multiple-comparison test are provided in Additional file 6. (f) The ratios of the number of Ca2+ events during the sq session to that in the pre session. Statistical values from Bonferroni’s multiple-comparison test are provided in Additional file 6 (n = 5 Wt mice, 4 Δβ mice). Data are means ± SEMs. No significant differences were observed (Kolmogorov–Smirnov test for panel c, Bonferroni’s multiple-comparison tests for panels d–f).

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