MOESM3 of Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

Additional file 3: Figure S3. Quantitation of cytoplasmic SOD-1 and HO-1 fluorescence induced by Methazolamide, Melatonin, and Trolox in the presence of PI3K- and GSK-3 inhibitors. Graphs in Panels A and B depict the quantitation of the cytoplasmic SOD-1 and HO-1fluorescence signal, respectively, of at least 400 cells utilizing ImageJ software and expressed in fold of control. Data is represented as mean ± SD; **** indicates p<0.0001.