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MOESM3 of Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation

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posted on 2019-10-18, 09:26 authored by Yi-Heng Hao, M. Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph DeBerardinis, Maralice Conacci-Sorrell
Additional file 3: Figure S3. (A) Gene levels of MYC-driven WNT signaling genes were compared between cancer tissues and normal tissues, and binary heatmaps were drawn to show the changes. Samples were sorted with p-value, and changes with p-value< 0.05 were considered statistically significant. (B) Kaplan–Meier curves comparing survival of various cancer types correlated with LEF1. Comparisons between 30% highest and 30% lowest expression were generated using ONCLnc ( http://www.oncolnc.org/ ).

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Cancer Prevention and Research Institute of Texas

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