MOESM3 of Human mesenchymal stem cells labelled with dye-loaded amorphous silica nanoparticles: long-term biosafety, stemness preservation and traceability in the beating heart

Additional file 3. (A-B) Representative images of morphological changes in UT (A) and SiO2-NPs -treated (B) hMSCs after 18 days of induced adipose differentiation. Arrows underline the presence of lipid vacuoles inside round differentiated cells. (C-D) UT (C) and SiO2-NPs -treated (D) hMSCs after 21 days of osteogenic differentiation. Cells are clearly immersed in a dense extracellular matrix. Magnification 10x, scale bar 100 µm.