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MOESM3 of Genome editing of oncogenes with ZFNs and TALENs: caveats in nuclease design

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posted on 2018-10-22, 05:00 authored by Sumitra Shankar, Ahalya Sreekumar, Deepti Prasad, Ani Das, M. Pillai
Additional file 3: Figure S3. In silico ZFN target site prediction for E7 using following tools did not yield suitable target sites. E6 gene was screened for possible ZFN pairs using (A) CoDa specific zinc fingers, (B) OPEN validated zinc fingers, (C) Sangamo validated modules, (D) TOOLGEN validated naturally occurring ZFN modules, (E) Barbas group of validated ZFN modules and F) ZFN predict.

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