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MOESM3 of Enhanced IFN-γ, but not IL-2, response to Mycobacterium tuberculosis antigens in HIV/latent TB co-infected patients on long-term HAART

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posted on 2019-10-11, 05:35 authored by Girmay Desalegn, Aster Tsegaye, Dawit Gebreegziabiher, Abraham Aseffa, Rawleigh Howe
Additional file 3: Figure S3. CD4+ T cell count increased with therapy duration after HAART but not correlated with M. tuberculosis specific IL-2 nor IFN-γ responses. (a) CD4+ T cell count before and after HAART in HAART-treated participants (n = 23). p value was determined using Mann-Whitney test. (b) Correlation between the number of increased CD4+ T cells with HAART and duration of therapy. Correlation of the number of CD4+ T cells gained after therapy with PPD and ESAT-6 specific IL-2 (c) and IFN-γ (d) responses in HAART-treated participants (n = 23). Spearman correlation was used to calculate correlation coefficients (rs) and p values.

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