12987_2019_150_MOESM3_ESM.tif (8.19 MB)

MOESM3 of Claudin-12 is not required for blood–brain barrier tight junction function

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posted on 12.09.2019, 04:08 by Mariana Castro Dias, Caroline Coisne, Pascale Baden, Gaby Enzmann, Lillian Garrett, Lore Becker, Sabine Hölter, Martin Hrabě de Angelis, Urban Deutsch, Britta Engelhardt
Additional file 3. Claudin-12 is expressed by different CNS cell types. Multi-color immunofluorescence staining of frozen brain sections from WT and claudin-12lacZ/lacZ C57BL/6J mice, for β-galactosidase in red and PECAM-1 (endothelial cells), PDGFRβ (pericytes), GFAP (astrocytes) and NeuN (neurons) in green, in the hippocampus and cerebellum. Nuclei are stained with DAPI (blue). β-gal stands for β-galactosidase. Two independent stainings were done. Scale bar = 50 μm.


European Union (EU) Seventh Framework Program FP7