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MOESM3 of Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2 V617F allelic burden

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posted on 2016-09-27, 05:00 authored by Magdalena Kovacsovics-Bankowski, Todd Kelley, Olga Efimova, Soo Kim, Andrew Wilson, Sabina Swierczek, Josef Prchal
Additional file 3: FigS3. Changes in numbers of Treg subsets in Peginfa treated patients based on molecular response. Patients treated with PegINFÎą were separated into R and NR subsets based on a 20% decrease in JAK2 V617 allelic burden. PBMC were analyzed as described above and fold changes compare to baseline were examined. Panel A represents 23 patient samples (10R and 13NR), panels B-C include 16 patients (6 R and 10 NR), and panel D includes 13 patients (4R and 9NR). A-C show the number of Treg, of dividing Treg, of CD39+ HLA-DR+ Treg and Helios+ Treg. Panel D shows CD38+ HLA-DR+ T cells in R vs NR.

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National Institutes of Health

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