MOESM2 of Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

Additional file 2: Figure S2. Quantitation of Nrf2 nuclear fluorescence induced by Methazolamide, Melatonin, and Trolox in the presence of PI3K- and GSK-3 inhibitors. Graph depicts the quantitation of Nrf2 nuclear fluorescence signal from images depicted in Figure 13. Fluorescence of at least 400 cells was quantitated utilizing ImageJ software and expressed in fold of control cells. Data is represented as mean ± SD; **** indicates p<0.0001.