12967_2016_875_MOESM2_ESM.tif (6.86 MB)
MOESM2 of Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin
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posted on 2016-05-10, 05:00 authored by Jason Hall, Laura Marlow, Adam Mathias, Louis Dawson, William Durham, Kenneth Meshaw, Robert Mullin, Aidan Synnott, Daniel Small, Murli Krishna, Daniel Hoff, Julia SchĂźler, Steven Hart, Fergus Couch, Gerardo Colon-Otero, John CoplandAdditional file 2: Figure S1. Expression Collagen I on Normal Pancreas and PACC. Collagen I borders acinar cell clusters and normal ductal structures. These borders were usually minimal in PA-018 unless treated with oxaliplatin, which restored expression of collagen I in certain regions of the PDTX tissue.