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MOESM2 of Long non-coding RNA PAXIP1-AS1 facilitates cell invasion and angiogenesis of glioma by recruiting transcription factor ETS1 to upregulate KIF14 expression

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posted on 2019-12-11, 10:44 authored by Haiyang Xu, Guifang Zhao, Yu Zhang, Hong Jiang, Weiyao Wang, Donghai Zhao, Hongquan Yu, Ling Qi
Additional file 2: Figure S2. LncRNA PAXIP1-AS1/ETS1/KIF14 axis affects the development of glioma in vivo. A, Representative images and volume quantitation of xenograft tumors. B, The weight quantitation of xenograft tumors. C, Western blot analysis of expression of E-Cadherin, N-Cadherin, MMP-2, VEGF-A, ETS1 and KIF14 normalized to GAPDH in xenograft tumors. D, The expression of CD31 examined by immunohistochemistry to calculate MVD in xenograft tumors (200 ×). * p < 0.05 vs. the oe-NC + sh-NC group, # p < 0.05 vs. the oe-PAXIP1-AS1 + oe-ETS1 + sh-NC group. The values are measurement data and expressed as mean ± standard deviation. Differences among multiple groups were compared by one-way ANOVA with Tukey’s post hoc test. Comparisons between time-based measurements were performed with repeated measures ANOVA, followed by Bonferroni post hoc test. N = 10.

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