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MOESM2 of Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation

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posted on 2019-10-18, 09:26 authored by Yi-Heng Hao, M. Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph DeBerardinis, Maralice Conacci-Sorrell
Additional file 2: Figure S2. (A) Comparison of the levels of the indicated genes in cancer tissues and adjacent normal tissues from TCGA database. Blue: downregulated (< 0.7), grey: no change (0.7–1.3), and red: upregulated (> 1.3). n = 41 pairs. (B) Kaplan–Meier curves comparing survival of patients with colon adenocarcinoma (COAD) divided into high and low expression levels of MYC-driven WNT signaling genes. Comparison between 30% highest and 30% lowest expression were generated using ONCLnc ( http://www.oncolnc.org/ ).

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Cancer Prevention and Research Institute of Texas

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