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MOESM2 of Closed system RT-qPCR as a potential companion diagnostic test for immunotherapy outcome in metastatic melanoma

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posted on 2019-09-19, 04:09 authored by Swati Gupta, Leena McCann, Yvonne Chan, Edwin Lai, Wei Wei, Pok Wong, James Smithy, Jodi Weidler, Brian Rhees, Michael Bates, Harriet Kluger, David Rimm
Additional file 2: Figure S2. RECIST category of objective response rate and multiplex RT-qPCR immunotherapy panel markers. (A) CD274, PDCD1LG2, CD8A, and IRF1 transcript expression. Data are presented as mean with standard deviation (error bars). (B) Predictive performance of CD274, PDCD1LG2, CD8A, and IRF1 transcript expression by ROC curves.

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    metastatic melanomaerror barsIRF 1 transcript expression1LGPDCDimmunotherapy outcomeobjective response rateMOESM 2ROC curvesRECISTmultiplex RT-qPCR immunotherapy panel markerssystem RT-qPCR8APredictive performance

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