MOESM1 of Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease

Additional file 1: Fig. S1. Comparative solubility and permeability of Cur or SLCP in vitro. A: schematic diagram of formulation of SLCP. Upper row: Solubility of Cur and SLCP in PBS. Note SLCP appeared to be more soluble in PBS, whereas Cur predominantly formed crystal-like structures. Middle and lower rows: The SLCP appeared to confer greater permeability than Cur in both N2a and 7-DIV primary hippocampal neurons after 2 h of incubation.