MOESM1 of Signatures of divergent anti-malarial treatment responses in peripheral blood from adults and young children in Malawi

Additional file 1. Additional methods. Figure S1. Manual gating strategy for quantifying monocyte subsets. Figure S2. Young age is associated with increases in blood-stage mature gametocytaemia during acute infection. Figure S3. Levels of gametocytaemia are similar in subjects with and without microscopically-detected parasitaemia. Figure S4. Plasmodium-specific antibody levels are higher in adults compared with young children regardless of visit. Figure S5. Correspondence between acute and post-treatment phenotypes. Figure S6. Q–Q plots of analyte phenotypes before and after Box-Cox-assisted power transformation. Table S1. Clinical characteristics of study participants (mean, interquartile range). Table S2. Results from anti-malarial antibody detection. Table S3. Table of p-values for main effects and interaction effects on blood analytes and cellular phenotypes, analysed using a nonparametric longitudinal model. Table S4. Table of p-values for main effects and interaction effects on blood analyte ratios. Table S5. Table of p-values for main effects and interaction effects on blood analytes, analysed using a linear mixed model.