MOESM1 of Radiosensitizing Effect of Gadolinium Oxide Nanocrystals in NSCLC Cells Under Carbon Ion Irradiation

Additional file 1: Figure S1. The hydrodynamic diameter of GONs was detected by dynamic light scattering. Figure S2. Cytotoxicity and cellular uptake of GONs. Figure S3. Original images of the relative cellular fluorescence intensity analyzed using ImageJ software. Figure S4. Flow cytometry images of cell cycle distribution in the three studied cell lines at 24 h after radiation. Figure S5. Flow cytometry images of the apoptotic rates. a The fluorescence images of single A549 cell detected by Amnis flow cytometry. b, c Flow cytometry images of the apoptotic rates of NH1299 (b) and NH1650 (c) cells at 48 h after carbon ion radiation. Figure S6. Flow cytometry images of autophagic rates at 12 h after radiation in A549 (a, d), NH1299 (b, e) and NH1650 (c, f) cells subjected to various treatments in the absence or presence of 3-MA.