MOESM1 of Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology

Additional file 1: Fig. S1. Evaluation of culture medium and comparison of Arctic and BL21 E. coli strains producing ΔNS1. Fig. S2 Effect of antifoam on the production of soluble ΔNS1. Fig. S3 Normal (%) probability plot of the Studentized residuals. Fig. S4 Reactivity of ΔNS1 and IgG antibodies from mouse infected with ZIKV and other viruses.