MOESM1 of Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 8 in patients with P. vivax infection

Additional file 1: Figure S1. Cytokine levels in supernatant of 72 hr splenocyte cultures of rPbMSP8-immunized BABL/C mice stimulated with PvMSP8 in vitro. (A) The levels (O.D. 450 nm) of splenocytes from mice immunized with rPvMSP8 after stimulation with 2.5 Îźg/mL of rPvMSP8. The asterisks indicate significant differences on the graph. (B) The levels of IFN-g, TNF-a, IL-2, IL-4, IL-10 cytokines from rPvMSP8-immunized mouse splenocytes stimulated with PvMSP8. Table S1. Peptide sequence information of overlapped 18-mer from the C terminus of PvMSP8. Table S2. Prevalence (% positive), 95% confidence intervals, and mean fluorescence intensity of IgG responses to rPvMSP8 in patient and healthy individual serum samples. Table S3. Prevalence, 95% confidence intervals, and normalized mean fluorescence intensity of IgG responses to rPvMSP8 in 1-month follow-up and archival sera samples.