Springer Nature
Browse
13073_2019_677_MOESM1_ESM.pdf (6.7 MB)

MOESM1 of NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants

Download (6.7 MB)
journal contribution
posted on 2019-10-23, 08:25 authored by Seong-Keun Yoo, Chang-Uk Kim, Hie Kim, Sungjae Kim, Jong-Yeon Shin, Namcheol Kim, Joshua Yang, Kwok-Wai Lo, Belong Cho, Fumihiko Matsuda, Stephan Schuster, Changhoon Kim, Jong-Il Kim, Jeong-Sun Seo
Additional file 1: Figure S1. Geographic map of the study area in the NARD. Figure S2. Correlation between the sequencing depth and number of variants. Figure S3. Transition to transversion ratio of the populations in the NARD. Figure S4. Heterozygous to homozygous ratio of the global populations. Figure S5. Number of loss-of-function variants. Figure S6. Hardy-Weinberg Equilibrium test of variants in the NARD. Figure S7. Novel variant statistics. Figure S8. Differential genetic composition of the two MNG groups. Figure S9. Imputation performance evaluation of FRA individuals. Figure S10. Imputation performance evaluation of CHN and JPN individuals. Figure S11. Length distribution of shared IBD tracts between the two individuals in each population. Figure S12. The flow chart of the pipeline consisting of four major steps for NARD imputation server. Figure S13. The cross-validation error inferred by ADMIXTURE algorithm.

Funding

Japan Agency for Medical Research and Development (AMED)

History

Usage metrics

    Genome Medicine

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC