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MOESM1 of Mechanical fibrinogen-depletion supports heparin-free mesenchymal stem cell propagation in human platelet lysate
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posted on 2015-11-10, 05:00 authored by Sandra Laner-Plamberger, Thomas Lener, Doris Schmid, Doris Streif, Tina Salzer, Michaela Öller, Cornelia Hauser-Kronberger, Thorsten Fischer, Volker Jacobs, Katharina Schallmoser, Mario Gimona, Eva RohdeAdditional file 1: Figure S1. MSC proliferation shown as cumulative population doublings (cPD). cPD have been calculated. The proliferative capacity of UC-MSCs, group 1 and of BM-MSCs, group 3 is comparable in the presence and absence of fibrinogen and heparin. In contrast, cPD of group 2 UC-MSCs show a significantly enhanced proliferation in response to heparin (group 2_C) compared to medium A and medium B. Data shown are mean values of cPD of three passages done in triplicates ± standard deviation (SD) of five (UC-MSCs) or three (BM-MSCs) independent donors.
