MOESM1 of Enhancing the production of cephalosporin C through modulating the autophagic process of Acremonium chrysogenum

Additional file 1: Table S1. Strains and plasmids used in this study. Table S2. Primers used in this study. Fig. S1. Verification of the heterologous complemented strains of ∆atg8 by RT-PCR. Fig. S2. Construction of the Acatg8 disruption mutant. Fig. S3. Localization of AcAtg8 during conidial germination of A. chrysogenum. Fig. S4. Relative transcriptional level of AcbrlA, AcwetA and AcabaA for conidiation in WT, ∆Acatg8 and Acatg8C. Fig. S5. Degradation of mitochondria in WT and ∆Acatg8. Fig. S6. Complementation of ∆Acatg8 with Acatg8 under control of xylP. Fig. S7. Inducible expression of Acatg8 under control of xylP. Fig. S8. Degradation of peroxisomes in WT and ∆Acatg8 during fermentation. Fig. S9. Degradation of CefD2 in WT and ∆Acatg8 during fermentation.