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MOESM1 of Early detection of the major male cancer types in blood-based liquid biopsies using a DNA methylation panel

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posted on 2019-12-03, 04:42 authored by Vera Constâncio, Sandra Nunes, Catarina Moreira-Barbosa, Rui Freitas, Jorge Oliveira, Inês Pousa, Júlio Oliveira, Marta Soares, Carlos Dias, Teresa Dias, Luís Antunes, Rui Henrique, Carmen Jerónimo
Additional file 1: Table S1. Associations between lung cancer patients’ clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels. p-values obtained by Mann-Whitney U Test. Table S2. Associations between prostate cancer patients’ clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels. p-values obtained by Mann-Whitney U Test for Primary Tumour (T) and Distant Metastasis (M), and by Kruskal-Wallis Test for Grade Group (GG), serum PSA levels and Clinical Stage. Table S3. Associations between colorectal cancer patients’ clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels. p-values obtained by Mann-Whitney U Test for Primary Tumour (T), Regional Node (N), Distant Metastasis (M) and Clinical Stage, and by Kruskal-Wallis Test for Tumour Location. Table S4. Demographics of the clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels in lung cancer patients, and their association with disease-specific mortality. p-values obtained by Gray’s test. Table S5. Demographics of the clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels in prostate cancer patients, and their association with disease-specific mortality. p-values obtained by Gray’s test. Table S6. Demographics of the clinicopathological features and APC, FOXA1, GSTP1, HOXD3, RARβ2, RASSF1A, SEPT9 and SOX17 promoters’ methylation levels in colorectal cancer patients, and their association with disease-specific mortality. p-values obtained by Gray’s test. Table S7. Primers and probes sequences with respective fluorochrome and quencher.

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Research Center - Portuguese Oncology Institute of Porto

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