MOESM1 of Combining directed evolution of pathway enzymes and dynamic pathway regulation using a quorum-sensing circuit to improve the production of 4-hydroxyphenylacetic acid in Escherichia coli

Additional file 1: Figure S1. (A) Esa quorum-sensing (QS) plasmid. (B) Activation and repression of genes using quorum-sensing circuit. Table S1. Mutations on the evolved gene. Table S2. The sequence of the TIGR.