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MOESM1 of Biomarkers and clinical scores to identify patient populations at risk of delayed antibiotic administration or intensive care admission

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posted on 30.10.2019, 18:13 by Juan Gonzalez del Castillo, Darius Wilson, Carlota Clemente-Callejo, Francisco Román, Ignasi Bardés-Robles, Inmaculada Jiménez, Eva Orviz, Macarena Dastis-Arias, Begoña Espinosa, Fernando Tornero-Romero, Jordi Giol-Amich, Veronica González, Ferran Llopis-Roca
Additional file 1: Table S1. Initial clinical diagnoses and suspected infectious source. Table S2. Characteristics of patients hospitalised at 72 h. Table S3. Univariate Logistic regression for antibiotic administration (ED treatment). Table S4. Univariate Logistic regression for hospitalisation requirement (ED presentation). Table S5. Univariate Logistic regression for ICU admission prediction (ED presentation). Table S6 Univariate Cox regression for the prediction of 28-day mortality (ED presentation). Table S7. Univariate Cox regression for the prediction of 28-day mortality (72 h). Table S8. Treatment and outcome in patients with low biomarker or score values (ED presentation). Table S9. Treatment and outcome in patients with high biomarker or score values (ED presentation). Table S10. Treatment and outcome in patients with low biomarker or score values (72 h). Table S11. Treatment and outcome in patients with high biomarker or score values (72 h). Table S12. Low NEWS patient subgroups classified according to Lactate and PCT kinetics between ED presentation and 72 h. Table S13. Patient subgroups stratified by lactate and MR-proADM. Table S14. Patient subgroups stratified by qSOFA and MR-proADM. Table S15. qSOFA and MR-proADM values upon presentation and 72 h within stratified subgroups. Table S16. Patient subgroups stratified by CRB-65 and MR-proADM. Table S17. Patient subgroups based on antibiotic administration using NEWS and MR-proADM. Table S18. Patient subgroups based on antibiotic administration using qSOFA and MR-proADM. Figure S1. AUROC analysis for antibiotic requirement during treatment within the ED. Figure S2. AUROC analysis for hospitalisation requirement upon ED presentation. Figure S3. AUROC analysis for ICU admission within 28 days of initial ED presentation. Figure S4. AUROC analysis for infection-related 28-day mortality upon ED presentation and 72 h.

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