MOESM1 of Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

Additional file 1: Table S1. Simon Broome diagnostic criteria for familial hypercholesterolemia. Table S2. Dutch Lipid Clinic Network Clinical Criteria for familial hypercholesterolemia. Table S3. Summary of pathogenic/likely pathogenic mutations in CAD patients. Table S4. Summary of variants of unknown significance in CAD patients. Table S5. Biochemical and clinical characteristics of patients in relation to DLCN Scores. Table S6. Plasma LDL-C levels stratified by genetic mutations in the patients with very early-onset CAD. Figure S1. Plasma LDL-C levels stratified by genetic mutations in the patients with very early-onset CAD. Figure S2. Percentage participants with CAD meeting clinical and genetic criteria for FH diagnosis. Table S7. Percentage participants with early-onset CAD meeting clinical and genetic criteria for FH diagnosis based on different initial LDL-C levels. Figure S3. Receiver operating characteristic curves of LDL-C (n = 105).