MOESM14 of Acute systemic inflammatory response to lipopolysaccharide stimulation in pigs divergently selected for residual feed intake

Additional file 14: Figure S6. Cross-validated representative profiles of genes responsive to LPS stimulation. Genes showing differential expression post LPS injection compared to baseline were cross-validated by using independent time-series gene expression microarray data studying pigs’ whole blood responses to LPS [23]. In Terenina et al. [23], DEGs showed delayed responses likely because a lower dosage of LPS was injected and/or injection sites were different. The y-axis shows the log2 fold change of gene expression at each time point relative to baseline, estimated by DESeq2 or limma. Smoothed expression profiles of individual genes per line were inferred by using LOWESS (Locally Weighted Scatterplot Smoothing). HRFI, high-RFI line; LRFI, low-RFI line; Normal, pigs not selected for RFI [23]. (PDF 101 kb)