40478_2020_881_MOESM11_ESM.mp4 (2.17 MB)

MOESM11 of A robust TDP-43 knock-in mouse model of ALS

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posted on 22.01.2020, 08:36 by Shih-Ling Huang, Lien-Szu Wu, Min Lee, Chin-Wen Chang, Wei-Cheng Cheng, Yu-Sheng Fang, Yun-Ru Chen, Pei-Lin Cheng, Che-Kun Shen
Additional file 11: Movie S3. 18-month old +/+ littermate of N390D/+ mouse (#361). Note the 18-month old N390D/+ mice (Additional file 9: Movie S1 and Additional file 10: Movie S2) but not +/+ littermate (Additional file 11: Movie S3) exhibit spastic and tremble gait. Some of them show difficult movement due to paralysis of the hind limbs (Additional file 10: Movie S2).

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