Additional file 9: of M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

Figure S4. The LINC00958/miR-3619-5p axis affects HCC progression through HDGF. (A) The efficiency of HDGF overexpression in LINC00958-silenced HCCLM3 cells was verified using RT-qPCR. (B) Western blotting was performed to validate the efficiency of HDGF overexpression in LINC00958-silenced HCCLM3 cells. (C) CCK-8 assays were conducted to evaluate the effects of HDGF overexpression on the proliferative ability of LINC00958-silenced HCCLM3 cells. The data are shown as the mean ± SEM. **P < 0.01 vs. the sh-NC group. (D) EdU assays were performed to analyze the effects of HDGF overexpression on Hep3B cells with LINC00958 knockdown. The data are shown as the mean ± SEM. **P < 0.01 vs. the sh-NC group. (E) Transwell assays were conducted to evaluate the effects of HDGF overexpression on the migration and invasion of LINC00958-silenced Hep3B cells. The data are shown as the mean ± SEM. **P < 0.01, ***P < 0.001 vs. the sh-NC group.