13059_2016_1045_MOESM9_ESM.pdf (269.92 kB)
Additional file 9: Figure S8. of Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
journal contribution
posted on 2016-09-19, 05:00 authored by Alex Genshaft, Shuqiang Li, Caroline Gallant, Spyros Darmanis, Sanjay Prakadan, Carly Ziegler, Martin Lundberg, Simon Fredriksson, Joyce Hong, Aviv Regev, Kenneth Livak, Ulf Landegren, Alex ShalekPCA separation of the various time points (0 hr = purple, 24 hr = green, 48 hr = blue). a A PCA over all quantitative protein targets and the corresponding ROC curves (b) for all three time points generated from random forest decision categorization with AUC of 0.98, 0.94, and 0.86 for 0 hr, 24 hr, and 48 hr, respectively. c A PCA over all quantitative RNA targets and the corresponding ROC curves (d) for all three time points generated from random forest decision categorization with AUC of 0.81, 0.80, and 0.57 for 0 hr, 24 hr, and 48 hr, respectively. e A PCA over all quantitative protein and RNA targets and the corresponding ROC curves (f) for all three time points generated from random forest decision categorization with AUC of 0.99, 0.94, and 0.84 for 0 hr, 24 hr, and 48 hr, respectively. For a, c, e, axis labels indicate which PC was used and what percent variance it explains. (PDF 269 kb)