Additional file 8: of Uncovering the trimethylamine-producing bacteria of the human gut microbiota

Abundance of cutC and cntA in healthy controls (C, n = 13) compared to symptomatic atherosclerosis patients (P, n = 12). Obtained p values (Mann-Whitney U test) are indicated. Raw metagenomic data from reference 12 was downloaded, subjected to adapter trimming (program trimmomatic from http://www.usadellab.org ) and quality filtering using the program fastq_quality_filter (-q 30 -p 50) from the FASTX-Toolkit ( http://hannonlab.cshl.edu/fastx_toolkit/ ), and reads were subsequently BLASTed against the cut/cnt gene databases developed here as described in the “Methods” section. (PDF 34 kb)