12915_2017_387_MOESM8_ESM.pdf (438.76 kB)
Additional file 8: of Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain
journal contribution
posted on 2017-06-29, 05:00 authored by Geena Skariah, Joseph Seimetz, Miles Norsworthy, Monica Lannom, Phillip Kenny, Mohamed Elrakhawy, Craig Forsthoefel, Jenny Drnevich, Auinash Kalsotra, Stephanie CemanRelated to Fig. 4. Mov10 binds mRNAs involved in actin cytoskeleton by RNA-seq. A) Screen shot from the sequencing of Mov10 exon2 in Mov10 KO N2a clone. Top panel is from WT Neuro2a. Bottom panel shows the mutant clone with the insertion generated by CRISPR-Cas9-mediated gene targeting. The mutation is boxed out. B) Gene Ontology (GO) analysis for Cellular Compartments from undifferentiated and differentiated WT Neuro2a. (See Additional file 9). (PDF 438 kb)