Additional file 8 of Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

Additional file 8: Figure S8. SERCA1a activators and RyR1 leak inhibitors increase maximal rates of relaxation in isolated mdx muscle. (A) Maximal rates of tetanic relaxation in isolated EDL muscle of C57BL/10 and mdx. (B) Maximal rates of tetanic relaxation in the EDL muscle of mdx mice following the addition of 1% DMSO (vehicle; p = 0.460), (C) 1.0 μM DS-11966966, (D) 100 μM CDN1163, (E) 0.1 μM Chloroxine and (F) 100 μM Myricetin. * Different from C57BL/10, # different from mdx. Data are mean ± S.E.M with significance set at p < 0.05. N = 4 – 22/compound.