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Additional file 7: of Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate

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posted on 2016-03-16, 05:00 authored by Aimin Li, Shudong Ma, Susan Smith, Matt Lee, Ashley Fischer, Zea Borok, Saverio Bellusci, Changgong Li, Parviz Minoo
Mesodermal progenitor-specific deletion of Pdgfrα. A. Quantitative PCR (Q-PCR) showed PDGF signaling target genes are decreased, indicating an overall functional repression of PDGFA signaling pathway in E14.5 Pdgfra Dermo1 lungs. n = 2 pairs of separate lungs, repeated twice or thrice. B. Q-PCR showed repression of myofibroblast-related genes in Pdgfra Dermo1 lungs. n = 2 pairs of separate lungs, repeated thrice for each. Error bars show SEM. (PPTX 68 kb)

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National Heart, Lung, and Blood Institute

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